lcsciences

LC Sciences provides a microRNA (miRNA) expression profiling service using microarrays based on our in-house-developed μParaflo® technology platform.   Circular RNAs (circRNAs) represent a novel class of abundant, stable, and ubiquitous RNA molecules. Unlike mRNAs, circRNAs lack poly (A) tails and 5’ caps, and are resistant to exonuclease degradation. circRNAs can act as microRNA (miRNA) or RNA-binding protein (RBP) sponges, sequestering miRNAs and sequestering these molecules and thereby regulating gene expression and transcriptional activity.   Circular RNA Sequencing (circrna seq) Advantages   Two options for library construction   The rRNA- library retained both circular and linear circrna sequencing, ensuring a comprehensive transcriptome analysis. The RNase ...

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Continuing advances in Sequencing Technologies, increases in the number of installed sequencers, and the decreasing cost of sequencing have all contributed to the generation of vast amounts of raw sequence data. This has led to perhaps the greatest challenge faced by scientists conducting sequencing experiments: the assembly and analysis of that data.   There is a growing backlog of sequence data resulting from the large amount of time, computing power, and expertise required to complete the data processing. At LC Sciences, we have rapid, standardized workflows in place for filtering, normalizing, the alignment, and statistical analysis of these often large and ...

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dia proteomics LC Sciences provides microRNA (miRNA) expression profiling services using microarrays based on our in-house-developed μParaflo® technology platform.   Astral, short for Asymmetric Track Lossless analyzer "Asymmetric", "Track" and "Lossless". The Orbitrap Astral mass spectrometer integrates a quadrupole, an Orbitrap, and a novel Asymmetric Track Lossless (Astral) mass analyzer. It delivers unprecedented processing speed, deeper proteome coverage, higher sensitivity, and superior quantitative accuracy, making it an landmark innovation in the Orbitrap series of mass spectrometers.   Astral DIA Proteomics Advantages   Higher throughput   Capable of analyzing 300 samples per day, with more than 8,000 proteins identified per sample.   Large-scale translational research   The Orbitrap Astral ...

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